临床治疗结果

世界各地的医疗团队针对UCP技术展开了大规模临床研究,为论证UCP技术的安全性以及有效性提供了大量可靠数据。

有效性

UCP技术已在全世界范围内治疗超过10 000名患者

术后12个月内眼压平均降低

基于6扇区治疗结果

术后12-18个月内的成功率为70-80%
 

*术后成功的标准:在无需新增降压药物的前提下,患者眼压下降幅度> 20%, 术后眼压> 5 mmHg,

有效性–重复治疗

« Clinical studies have shown the overall procedure efficacy to improve after multiple UCP treatments » 1
 
 
« Repeated UCP has to be considered in patients with target IOP not reached, and in patients with early or delayed IOP increase» 2

资料来源:Safety and efficacy of multiple cyclocoagulation of ciliary bodies by high-intensity focused ultrasound in patients with glaucoma – Dra De Gregorio & All – Graefe’s Archives for clinical and experimental ophthalmology – October 2017

资料来源 : Aptel F et al. Efficacy and safety of repeated Ultrasound Cycloplasty procedures in patients with early or delayed failure after a first procedure. J Glaucoma, 2020 Jan; 29(1):24-30

安全性

众多临床研究显示UCP技术良好的安全性,未出现严重不良反应

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临床研究

Ultrasound Cyclo Plasty for Treatment of Surgery-Naïve Open-Angle Glaucoma Patients: A Prospective, Multicenter, 2-Year Follow-Up Trial
Journal of Clinical Medecine 2021, J. Clin. Med. 2021, 10(21), 4982

Michele Figus,Chiara Posarelli, Marco Nardi, Ingeborg Stalmans, Evelien Vandewalle, Shlomo Melamed, Alon Skaat, Ari Leshno, David Cordeiro Sousa and Luis Abegão Pinto

High-intensity focused ultrasound in the treatment of glaucoma: a narrative review
Expert Review of Ophthalmology, Volume 10,2021 - Issue 3 - Pages 161-174
 
Michele Figus, Francesco Sartini, Giuseppe Covello & Chiara Posarelli

Efficacy and Safety of Ultrasound Cycloplasty for Refractory Glaucoma: A 3-Year Study
Journal of Glaucoma 2021, May 2021 - Volume 30 - Issue 5, p428-435

Rouland, Jean-François MD, FEBO*; Aptel, Florent MD, PhD†

A 2-year prospective multicenter study of ultrasound cyclo plasty for glaucoma
Scientific Reports volume 11, Article number: 12647 (2021)

Giannaccare G, Pellegrini M, Bernabei F, Urbini L, Bergamini. F, Desideri LF, Bagnis A, Biagini F, Cassottana P, Del Noce C, Carnevali A, Scorcia V, Traverso CE, Vagge A. 

Efficacy and safety of repeated ultrasound cycloplasty procedures in patient with early or delayed failure after a first procedure

Journal of Glaucoma: January 2020 - Volume 29 - Issue 1 - p 24-30

Aptel, Florent MD, PhD*; Tadjine, Mehdi MD*; Rouland, Jean-François MD†

The Influence of Ultrasound Ciliary Plasty on Corneal Parameters
Journal of Glaucoma: October 2020 - Volume 29 - Issue 10 - p 899-904

Bolek, Bartłomiej MD; Wylęgała, Adam MD, PhD; Wylęgała, Edward MD, PhD

High intensity focused ultrasound for glaucoma: 1-year results from a prospective pragmatic study
Eye - Volume 35, pages 484–489 (2021)

Raquel E. Marques, Nuno P. Ferreira, David C. Sousa, André Diogo Barata, Paula Sens, Carlos Marques-Neves & Luis Abegão Pinto

Safety and efficacy of ultrasound ciliary plasty as a primary intervention in glaucoma patients
International Journal of Ophthalmology, Volume 12, No. 4, Apr.18, 2019

Magda A. Torky, Yousif A Al Zafri , Sherein M. Hagras , Abeer M. Khattab , Rania M. Bassiouny , Tharwat H. Mokbel

 
Application of high intensity focused ultrasound for treatment of open-angle glaucoma In Indian patients
Indian Journal of Ophthalmology - Vol 66, Issue 4, April 2018

Nilanjana Deb‑Joardar, Kasu Prasad Reddy

Safety and efficacy of multiple cyclocoagulation of ciliary bodies by high-intensity focused ultrasound in patients with glaucoma
Graefe's Archive for Clinical and Experimental Ophthalmology - Volume 255, pages2429–2435 (2017)

Alessandra De Gregorio & Emilio Pedrotti & Giulia Stevan & Margherita Montali  & Simonetta Morselli